发明名称 |
REVERSIBLE ATTACHMENT OF A MEMBRANE ACTIVE POLYMER TO A POLYNUCLEOTIDE |
摘要 |
Described is a process for delivering a biologically active compound to a cell by reversibly linking the compound to a membrane active polymer. In particular, polymer-polynucleotide conjugates are described. Methods for reversibly modifying the polymers to decrease cellular toxicity and improve efficacy are provided. |
申请公布号 |
WO2004074509(A3) |
申请公布日期 |
2005.10.13 |
申请号 |
WO2004US04493 |
申请日期 |
2004.02.18 |
申请人 |
MIRUS CORPORATION |
发明人 |
ROZEMA, DAVID, B.;WAKEFIELD, DARREN |
分类号 |
A01N43/04;A61K9/127;A61K47/48;A61K48/00;C12N15/11;C12Q;C12Q1/00 |
主分类号 |
A01N43/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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