发明名称 |
USE OF TWO-PHOTON EXCITED FLUORESCENCE IN ASSAYS OF CLINICAL CHEMISTRY ANALYTES |
摘要 |
The invention relates to an in vitro diagnostic method for quantification of a clinical chemistry analyte from a clinical sample wherein the clinical chemistry analyte undergoes a chemical reaction or reactions with a reagent or reagents in one or several steps, or in a reaction sequence, or catalyses a chemical reaction, or reactions, or a reaction in a reaction sequence of a reagent or reagents, in one or several steps, in a reaction system. The reaction or reactions or reaction sequence result in a change of a measurable property of a compound or compounds of said reaction or reactions or reaction sequence. Characteristic for the method is that said chemical reaction or reactions or reaction sequence results in formation of a two-photon fluorescent compound, or a change in two-photon fluorescence properties of the reaction system comprising at least one two-photon fluorescent compound, and the analyte is quantified by exciting said two-photon fluorescent compound or compounds and measuring two-photon excited fluorescence, and relating said measured fluorescence to method standardization data based on measurements obtained from reference material of said analyte. |
申请公布号 |
WO2005078438(A3) |
申请公布日期 |
2005.10.13 |
申请号 |
WO2005FI50028 |
申请日期 |
2005.02.11 |
申请人 |
ARCTIC DIAGNOSTICS OY;SOINI, ERKKI;SOINI, ALEKSI;SOINI, JUHANI;MELTOLA, NIKO |
发明人 |
SOINI, ERKKI;SOINI, ALEKSI;SOINI, JUHANI;MELTOLA, NIKO |
分类号 |
G01N;G01N21/64;G01N33/53;G01N33/58 |
主分类号 |
G01N |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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