| 摘要 |
<P>PROBLEM TO BE SOLVED: To identify an articular rheumatism-sensitive gene by a mapping method using a high-efficiency and low-cost microsatellite. <P>SOLUTION: The new articular rheumatism-sensitive gene of the TNXB, NOTCH4, RAB6A, MPRL48, UCP2 or UCP3 gene of a human genome sequence is identified by carrying out a case control correlation analysis corresponding to the articular rheumatism by using a microsatellite polymorphism marker set at about 100 kb interval to narrow down a candidate range, and carrying out a correlation analysis and a linkage analysis using SNP as a marker. <P>COPYRIGHT: (C)2006,JPO&NCIPI |
