发明名称 |
BIOMARKERS AND METHODS FOR DETERMINING SENSITIVITY TO EPIDERMAL GROWTH FACTOR RECEPTOR MODULATORS IN NON-SMALL CELL LUNG CANCER |
摘要 |
EGFR biomarkers useful in a method for identifying a mammal that will respon d therapeutically to a method of treating cancer comprising administering an EGFR modulator, wherein the method comprises (a) exposing a biological sampl e from the mammal to the EGFR modulator and (b) measuring in the biological sample the level of the at least one biomarker, wherein a difference in the level of the at least one biomarker measured in (b) compared to the level of the biomarker in a mammal that has not been exposed to the EGFR modulator indicates that the mammal will respond therapeutically to the method of treating cancer.
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申请公布号 |
CA2561111(A1) |
申请公布日期 |
2005.10.13 |
申请号 |
CA20052561111 |
申请日期 |
2005.03.28 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
PERKINS, NANCY-ANNE;FORD, SHIRIN K.;JACKSON, DONALD G. |
分类号 |
C12Q1/68;A61K39/395;A61K49/14;C07K16/28 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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