Fibrosis inhibitor

摘要

Medicament being useful as a fibrosis inhibitor for organs or tissues, which comprises a compound of the formula (I): wherein Ring Z is optionally substituted pyrrole ring, etc.; W² is -CO-, -SO₂-, optionally substituted C₁-C₄ alkylene, etc.; Ar² is optionally substituted aryl, etc.; W¹ and Ar¹ mean the following (1) and (2): (1) W¹ is optionally substituted C₁-C₄ alkylene, etc.; Ar¹ is optionally substituted bicyclic heteroaryl having 1 to 4 nitrogen atoms as ring-forming atoms: (2) W¹ is optionally substituted C₂-C₅ alkylene, optionally substituted C₂-C₅ alkenylene, etc.; and Ar¹ is aryl or monocyclic heteroaryl, which is substituted by carboxyl, alkoxycarbonyl, etc. at the ortho- or meta-position thereof with respect to the binding position of W₁, or a pharmaceutically acceptable salt thereof.