| 摘要 |
A novel anti-itching agent useful for the treatment of itches accompanying various diseases. The anti-itching agent contains as an active ingredient a morphinan derivative having a specific nitrogenous cyclic substituent or a pharmacologically acceptable acid addition salt thereof, such as, e.g., N-(1 7- cyclopropylmethyl-4,5.alpha.-epoxy-3,14-dihydroxymorphinan-6.beta.- yl)phthalimide hydrochloride, [Chemical formula 1] (1) or N-(17- cyclopropylmethyl-4,5.alpha.-epoxy-3,14-dihydroxy~morphinan-6.beta.-yl)- 3,4,5,6-tetrahydrophthalimide tartrate.
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