COMPOSITIONS AND METHODS FOR DIAGNOSTICS AND THERAPEUTICS FOR HYDROCEPHALUS
摘要
The present disclosure relates to RFX4_v3 protein and nucleic acids encoding RFX4_v3 protein. The present disclosure provides non-human transgenic animals with altered RFX4_v3 genes, and provides assays for the detection of RFX4_v3 and RFX4_v3 polymorphisms associated with disease states. The present disclosure additionally provides methods of determining a subjects' risk of developing congenital hydrocephalus, and treating or inhibiting its development.
申请公布号
WO03088919(A3)
申请公布日期
2005.10.13
申请号
WO2003US12348
申请日期
2003.04.18
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS;BLACKSHEAR, PERRY, J.;ZELDIN, DARRYL C.;GRAVES, JOAN P.;STUMPO, DEBORAH J.
发明人
BLACKSHEAR, PERRY, J.;ZELDIN, DARRYL C.;GRAVES, JOAN P.;STUMPO, DEBORAH J.