ANTIBODY DRUG

摘要

An ameliorating agent for the stability of mammalian endogenous ligand in the blood, comprising an antibody having affinity with mammalian endogenous ligand and substantially not neutralizing the same; and preparations thereof for the prevention and treatment of diseases in accomplishment of which it is effective to increase the concentration of endogenous ligand in the blood and/or prolong the half life period thereof in the blood. When the preparations alone without being combined with a compound identical with or substantially identical with the endogenous ligand are administered to a mammal, the stability of endogenous ligand in the blood would be enhanced to thereby reinforce the receptor activity regulating action thereof.