PROCESS FOR REDUCING THE NUMBER OF MISMATCHES IN DOUBLE STRANDED POLYNUCLEOTIDES

摘要

The present invention relates to a process for reducing the number of mismatches in a population of double stranded polynucleotides. Furthermore, the present invention relates to a process of producing double stranded polynucleotides. Also, the invention is directed to the use of an enzymes that cleaves and/or removes cleaved mismatches in double stranded polynucleotides in a process according to the invention as well as a kit of parts.