发明名称 Process for the synthesis of 1,3-dihydro-2H-3-benzazepin-2-one compounds, and to the application thereof in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
摘要 Process for the synthesis of compounds of formula (I): wherein R<SUB>1 </SUB>and R<SUB>2</SUB>, which may be the same or different, each represent a linear or branched (C<SUB>1</SUB>-C<SUB>8</SUB>)alkoxy group or form, together with the carbon atom carrying them, a 1,3-dioxane, 1,3-dioxolane or 1,3-dioxepane ring. Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid, and hydrates thereof.
申请公布号 US2005227962(A1) 申请公布日期 2005.10.13
申请号 US20050057491 申请日期 2005.02.14
申请人 LERESTIF JEAN-MICHEL;LECOUVE JEAN-PIERRE;BRIGOT DANIEL 发明人 LERESTIF JEAN-MICHEL;LECOUVE JEAN-PIERRE;BRIGOT DANIEL
分类号 C07D223/16;C07D405/06;(IPC1-7):A61K31/55;C07D45/02 主分类号 C07D223/16
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