| 发明名称 |
HUMAN ANTI-FACTOR IX/IXA ANTIBODIES |
| 摘要 |
Human antibodies, or fragments thereof, to the gamma-carboxyglutamic acid (Gla) domain of factor IX and factor IXa, especially of human factor IX and human factor IXa. Isolated nucleic acid encoding said antibodies or fragments thereof. Methods for their preparation. Pharmaceutical composition comprising said antibodies or fragments thereof, and a method for treating a mammal by using said pharmaceutical composition in a therapeutically effective amount.</SDOA B> |
| 申请公布号 |
CA2341276(C) |
申请公布日期 |
2005.10.11 |
| 申请号 |
CA19992341276 |
申请日期 |
1999.08.26 |
| 申请人 |
GENENTECH, INC. |
发明人 |
DEVAUX, BRIGITTE;ADAMS, CAMELLIA W.;KIRCHHOFER, DANIEL;JUDICE, J. KEVIN;SUGGETT, SHELLEY;HASS, PHILIP E.;EATON, DAN L. |
| 分类号 |
G01N33/50;A61K38/00;A61K39/395;A61P7/02;A61P9/02;A61P9/10;A61P11/00;A61P39/02;C07K16/36;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/13;C12N15/63;C12P21/02;C12P21/08;G01N33/15 |
主分类号 |
G01N33/50 |
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