发明名称 |
Derivatives of partially desulphated glycosaminoglycans endowed with antiangiogenic activity and devoid of anticoagulating effect |
摘要 |
Partially desulfated glycosaminoglycan derivatives are described, particularly heparin, and more particularly formula (I) compounds where the U, R and R<SUB>1 </SUB>groups have the meanings indicated in the description. These glycosaminoglycan derivatives exhibit antiangiogenic activity and are devoid of anticoagulant activity.
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申请公布号 |
US2005222084(A1) |
申请公布日期 |
2005.10.06 |
申请号 |
US20050028512 |
申请日期 |
2005.01.04 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
CASU BENITO;TORRI GIANGIACOMO;NAGGI ANNA M.;GIANNINI GIUSEPPE;PISANO CLAUDIO;PENCO SERGIO |
分类号 |
C12P19/04;A61K31/7024;A61K31/726;A61K31/727;A61P3/10;A61P9/08;A61P17/06;A61P27/02;A61P35/00;C07H11/00;C08B37/00;C08B37/10;(IPC1-7):C08B37/10 |
主分类号 |
C12P19/04 |
代理机构 |
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代理人 |
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地址 |
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