9-SUBSTITUTED 8-OXOADENINE COMPOUND

摘要

An 8-oxoadenine compound represented by the formula (1): [wherein ring A represents a 6- to10-membered aromatic carbocycle, etc.; R represents halogeno, alkyl, etc.; n is an integer of 0 to 2; Z<1> represents alkylene; X<2> represents oxygen, sulfur, SO2, NR<5>, CO, CONR<5>, NR<5>CO, etc.; Y<1>, Y<2>, and Y<3> each independently represents a single bond or alkylene; X<1> represents oxygen, sulfur, NR<4> (wherein R<4> represents hydrogen or alkyl), or a single bond; R<2> represents (un)substituted alkyl, etc.; and R<1> represents hydrogen, hydroxy, alkoxy, alkoxycarbonyl, haloalkyl, etc.] or a pharmaceutically acceptable salt thereof. They have immunoregulatory activity such as interferon-inducing activity and are useful as an antiviral agent, antiallergic, etc.