Thiazole sulfonamide compounds for the treatment of neurodegenerative disorders

摘要

The present invention relates to compounds of the Formula: wherein R¹ to R⁶, X, Z and A are as defined. These compounds have activity inhibiting production of Abeta-peptide. The invention also relates to pharmaceutical compositions and methods for treating diseases, for example, neurodegenerative diseases, e.g., Alzheimer's disease, in a mammal comprising compounds of the present Formula.