发明名称 Hybrid and tandem expression of neisserial proteins
摘要 Two or more Neisserial proteins are joined such that they are translated as a single polypeptide chain. Hybrid proteins are represented by the formula NH<SUB>2</SUB>-A-[-X-L-]<SUB>n</SUB>-B-COOH where X is an amino acid sequence, L is an optional linker amino acid sequence, A is an optional N-terminal amino acid sequence, B is an optional C-terminal amino acid sequence, and n is an integer greater than 1. Proteins where each of the n -X- moieties shares sequence identity to each other -X- moiety, the protein is a 'tandem protein'.
申请公布号 US2005222385(A1) 申请公布日期 2005.10.06
申请号 US20050488786 申请日期 2005.02.25
申请人 CHIRON SPA 发明人 PIZZA MARIAGRAZIA
分类号 C12N15/09;A61K39/00;A61K39/08;A61K39/085;A61K39/09;A61K39/095;A61K39/102;A61K39/106;A61K39/118;A61K39/13;A61K39/145;A61K39/165;A61K39/205;A61K39/29;C07H21/00;C07K14/195;C07K14/22;C07K19/00;C12N15/10;(IPC1-7):C07K14/22;A61K39/02;C07H21/04 主分类号 C12N15/09
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