发明名称 |
C-6 modified indazolylpyrrolotriazines |
摘要 |
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
|
申请公布号 |
US2005222153(A1) |
申请公布日期 |
2005.10.06 |
申请号 |
US20050143279 |
申请日期 |
2005.06.02 |
申请人 |
VITE GREGORY D;GAVAL ASHVINIKUMAR V;FINK BRIAN E;MASTALERZ HAROLD;KADOW JOHN F |
发明人 |
VITE GREGORY D.;GAVAL ASHVINIKUMAR V.;FINK BRIAN E.;MASTALERZ HAROLD;KADOW JOHN F. |
分类号 |
A61K;A61K31/53;A61P13/08;A61P19/02;A61P29/00;A61P37/00;C07D;C07D487/02;C07D487/04;(IPC1-7):A61K31/53 |
主分类号 |
A61K |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|