发明名称 |
Peptide compositions with effects on blood glucose |
摘要 |
The present invention provides compositions and methods for ameliorating neurological or memory disorders and improving learning and cognition through the increase of cyclic AMP. Gilatides, peptides comprising the nine amino acid sequence (SEQ ID NO:1), and functional analogs thereof are disclosed to modulate neurological activity when administered to a subject. The methods of the invention can be used to prevent or treat neurological disorders as well as improve memory retention and acquisition. In addition, the invention can be used to modulate insulin levels and blood glucose. The invention includes pharmaceutical compositions comprising a therapeutically or prophylactically effective amount of a Gilatide peptide or a functional analog thereof.
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申请公布号 |
US2005222036(A1) |
申请公布日期 |
2005.10.06 |
申请号 |
US20030405089 |
申请日期 |
2003.04.01 |
申请人 |
THOMAS JEFFERSON UNIVERSITY |
发明人 |
DURING MATTHEW J.;HAILE COLIN N.;CAO LEI |
分类号 |
A61K38/00;C07K14/575;C07K14/605;(IPC1-7):A61K38/08 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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