A FORMULATION FOR INCREASING ENDOGENOUS ADIPONECTIN AND LEPTIN PRODUCTION
摘要
A formulation for and method of enhancing adiponectin and leptin secretion is disclosed. The method comprises contacting living cells with an inhibitor of the enzyme pyruvate dehydrogenase kinase (PDHK). The PDHK inhibitor causes the cells it contacts to increase adiponectin secretion as well as increasing the production of leptin. The increased levels of adiponectin alone (or in a synergistic combination with increased leptin) provides a range of desired results including weight loss and the prevention of weight.
申请公布号
WO2005092040(A2)
申请公布日期
2005.10.06
申请号
WO2005US09395
申请日期
2005.03.22
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;LEPTOGEN, INC.;HAVEL, PETER, J.;STANHOPE, KIMBER, L.;EVANS, JOSEPH, L.
发明人
HAVEL, PETER, J.;STANHOPE, KIMBER, L.;EVANS, JOSEPH, L.