发明名称 |
Binding of pathological forms of prion proteins |
摘要 |
Infective aggregating forms of proteins such as PrP, amyloid, and tau are bound selectively in the presence of the normal form protein using a polyionic binding agent such as dextran sulphate or pentosan (anionic), or polyamine compounds such as pDADMAC (cationic) under selective binding conditions including the use of n-lauroylsarcosine at mildly alkaline pH, and may then be assayed.
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申请公布号 |
US2005221404(A1) |
申请公布日期 |
2005.10.06 |
申请号 |
US20040506131 |
申请日期 |
2004.08.27 |
申请人 |
LANE AMIN R;STANLEY CHRISTOPHER J;WILSON STUART M |
发明人 |
LANE AMIN R.;STANLEY CHRISTOPHER J.;WILSON STUART M. |
分类号 |
G01N33/68;C07K1/22;C07K14/47;G01N33/53;(IPC1-7):G01N33/53;G01N33/537;G01N33/543 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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