Par-2-activating peptide derivative and pharmaceutical composition using the same

摘要

The present invention relates to a peptide derivative represented by the general formula (I) or a salt thereof: Z-(CH₂)_n-CO-NH-Leu-Ile-Gly-AA₁-AA₂-CO-R (I) wherein Z represents an aryl group which may or may not have a substituent or a heteroaryl group which may or may not have a substituent; n represents 0, 1 or 2: AA₁-AA₂ represents Lys-Val or Arg-Leu; and R represents -OH or -NH₂, and relates to a pharmaceutical composition comprising a peptide derivative represented by the general formula (I) or a salt thereof, and a pharmaceutically acceptable carrier thereof.