| 发明名称 |
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors |
| 摘要 |
Disclosed is a novel enantiomeric synthesis ceramide-like inhibitors of UDP-glucose: N-acylsphingosine glucosyltransferase. Also disclosed are novel intermediates formed during the synthesis.
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| 申请公布号 |
US2005222244(A1) |
申请公布日期 |
2005.10.06 |
| 申请号 |
US20050091836 |
申请日期 |
2005.03.28 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
SIEGEL CRAIG;SHAYMAN JAMES A.;NELSON CAROL A.;HARRIS DAVID J.;COPELAND DIANE P. |
| 分类号 |
C07D295/12;A61K31/40;A61K31/4025;A61P1/16;A61P7/06;A61P17/02;A61P25/28;A61P27/02;A61P35/00;A61P43/00;C07B53/00;C07B61/00;C07D295/18;C07D295/185;C07D319/18;C07D498/04;(IPC1-7):A61K31/402;C07D45/02 |
主分类号 |
C07D295/12 |
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