发明名称 PROCESS FOR THE PREPARATION OF 3-AMINO-8-(1-PIPERAZINYL) -2H-1-BENZOPYRAN-2-ONE AND SALTS AND HYDRATES THEREOF
摘要 The invention relates to a novel process for the preparation of 3-amino-8- (1~piperazinyl)-2H-1-benzopyran-2-one, a broad spectrum 5-HT receptor bindin g ligand having potent 5-HT1A-agonistic as well as 5-HT1D-antagonistic activit y. The invention also relates to novel salts and solvates, in particular hydrat es of salts of said compound, as well as to their use as medicaments. The invention relates the compounds with the formula (7).
申请公布号 CA2554041(A1) 申请公布日期 2005.10.06
申请号 CA20052554041 申请日期 2005.03.23
申请人 SOLVAY PHARMACEUTICALS B.V. 发明人 BAKKER, CORNELIS
分类号 A61K31/496;A61P25/00;C07D311/18 主分类号 A61K31/496
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