发明名称 |
New use of pyrimidine - or triazine - 2 carbonitiles for treating diseases associated with cysteine prostease activity and novel pyrimidine-2-carbonitile derivatives |
摘要 |
The present invention therefore provides use of a compound of formula (I) and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases S, K, F, L and B. Of particular interest are diseases associated with Cathepsin S. In addition, this invention also discloses processes for the preparation of such inhibitors.
|
申请公布号 |
US2005222152(A1) |
申请公布日期 |
2005.10.06 |
申请号 |
US20040518817 |
申请日期 |
2004.12.20 |
申请人 |
BAILEY ANDREW;PAIRAUDEAU GARRY;PATEL ANIL;THOM STEPHEN |
发明人 |
BAILEY ANDREW;PAIRAUDEAU GARRY;PATEL ANIL;THOM STEPHEN |
分类号 |
A61K31/506;A61K31/53;A61K31/5377;A61P9/00;A61P11/00;A61P11/06;A61P19/02;A61P19/10;A61P25/00;A61P25/28;A61P29/00;A61P37/00;A61P43/00;C07D239/46;C07D239/48;C07D239/50;C07D251/18;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D405/04;C07D405/12;C07D413/14;C07D487/08;(IPC1-7):A61K31/53;A61K31/513;A61K31/505 |
主分类号 |
A61K31/506 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|