发明名称 |
Dual inhibition of cyclooxygenase-2 and carbonic anhydrase |
摘要 |
Compounds of Formula I potently inhibit both cyclooxygenase-2 and carbonic anhydrases. Inhibition of carbonic anhydrases by a cyclooxygenase-2 inhibitor may affect significantly the safety and efficacy profiles of such a dual inhibitor in the treatment of cyclooxygenase-2 mediated disorders, compared to a cyclooxygenase-2 inhibitor without carbonic anhydrase inhibitory activity.
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申请公布号 |
US2005222251(A1) |
申请公布日期 |
2005.10.06 |
申请号 |
US20050091376 |
申请日期 |
2005.03.29 |
申请人 |
AMOREPACIFIC CORPORATION |
发明人 |
PARK MI-YOUNG;LIM KYUNG-MIN;SHIN SONG-SEOK;HA JUN-YONG;CHUNG SHIN |
分类号 |
A61K31/34;A61K31/341;A61P29/00;(IPC1-7):A61K31/34 |
主分类号 |
A61K31/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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