发明名称 |
Topical anhydrous and ethanol-free ascomycin compositions |
摘要 |
Single-phase topical liquid or semi-solid pharmaceutical compositions substantially free of ethanol and water and comprising an ascomycin, such as pimecrolimus, in a carrier vehicle comprising a 3-component solvent mixture amounting to at least 40% w/w of the total weight of the composition and consisting of: i) a C<SUB>3-8 </SUB>alkanol and/or C<SUB>1-8 </SUB>alkanediol; ii) a fatty alcohol; and iii) a further solvent selected from: a) an alkane carboxylic acid alkyl ester and/or alkane dicarboxylic acid alkyl ester and/or b) a hydrophilic co-component and/or c) a triglyceride; and optionally further conventional excipients.
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申请公布号 |
US2005220850(A1) |
申请公布日期 |
2005.10.06 |
申请号 |
US20050523750 |
申请日期 |
2005.02.08 |
申请人 |
LEDERGERBER DOROTHEA;SONNTAG JEAN-CLAUDE;KRIWET KATRIN;SEKKAT NABILA |
发明人 |
LEDERGERBER DOROTHEA;SONNTAG JEAN-CLAUDE;KRIWET KATRIN;SEKKAT NABILA |
分类号 |
A61K9/06;A61K9/10;A61K31/445;A61K31/706;A61K47/02;A61K47/04;A61K47/06;A61K47/10;A61K47/14;A61K47/26;A61K47/38;A61K47/44;A61K47/46;A61P17/00;(IPC1-7):A61K31/33;A61K9/00 |
主分类号 |
A61K9/06 |
代理机构 |
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