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发明名称 INHIBITORS OF HISTONE DEACETYLASE
摘要 The invention relates to a series of compounds useful for inhibiting histone deacetylase (HDAC) enzymatic activity. The invention also provides a method for inhibiting histone descetylase in a cell using said compounds as well as a method for treating cell proliferative diseases and conditions using said HDAC inhibitors. Further, the invention provides pharmaceutical compositions comprising the HDAC inhibiting compounds and a pharmaceutically acceptable carrier.
申请公布号 WO2005092899(A1) 申请公布日期 2005.10.06
申请号 WO2005CA00454 申请日期 2005.03.29
申请人 METHYLGENE INC.;DELORME, DANIEL;VAISBURG, ARKADII;MORADEI, OSCAR;LEIT, SILVANA;RAEPPEL, STEPHANE;FRECHETTE, SYLVIE;BOUCHAIN, GILIANE;ZHOU, ZHIHONG;PAQUIN, ISABELLE;GAUDETTE, FREDERIC;ISAKOVIC, LJUBOMIR 发明人 DELORME, DANIEL;VAISBURG, ARKADII;MORADEI, OSCAR;LEIT, SILVANA;RAEPPEL, STEPHANE;FRECHETTE, SYLVIE;BOUCHAIN, GILIANE;ZHOU, ZHIHONG;PAQUIN, ISABELLE;GAUDETTE, FREDERIC;ISAKOVIC, LJUBOMIR
分类号 A61K31/343;A61K31/36;A61K31/40;A61K31/428;A61K31/4439;A61K31/455;A61K31/496;A61K31/505;A61K31/5377;C07C237/40;C07D209/08;C07D209/14;C07D209/16;C07D213/22;C07D213/38;C07D213/74;C07D231/38;C07D235/16;C07D237/20;C07D239/26;C07D239/42;C07D239/48;C07D263/58;C07D271/06;C07D277/68;C07D277/74;C07D277/82;C07D295/092;C07D295/135;C07D295/185;C07D307/85;C07D333/38;C07D401/04;C07D401/12;C07D403/04;C07D403/12;C07D409/04;C07D413/10;C07D413/12;C07D417/04;C07D417/12;C07D471/04;C07D495/04 主分类号 A61K31/343
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