发明名称 |
Use of farnesyl protein transferase inhibitor for the preparation of pharmaceutical composition having radiosensitizing properties |
摘要 |
Use of farnesyl protein transferase inhibitor for the preparation of pharmaceutical composition having radiosensitizing properties for administration before, during or after irradiation of a tumour for treating tumour in vivo, wherein farnesyl protein transferase inhibitor is a compound of formula (I), or compound of formula (II), or (III), which is metabolized to compound of formula (I) in vivo, wherein the dotted line represents an optional bond; X is oxygen or sulphur and other symbols have the meaning stated in claims. |
申请公布号 |
SK284723(B6) |
申请公布日期 |
2005.10.06 |
申请号 |
SK20000001986 |
申请日期 |
1999.06.30 |
申请人 |
JANSSEN PHARMACEUTICA N. V. |
发明人 |
VAN GINCKEL ROBERT FRANCISCUS;FLOREN WIM JOANNA;END DAVID WILLIAM;WOUTERS WALTER BOUDEWIJN LEOPOLD |
分类号 |
C07D401/06;A61K31/4709;A61K41/00;A61P35/00;A61P43/00;C07D401/14;C07D405/14;C07D413/14 |
主分类号 |
C07D401/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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