发明名称 Use of farnesyl protein transferase inhibitor for the preparation of pharmaceutical composition having radiosensitizing properties
摘要 Use of farnesyl protein transferase inhibitor for the preparation of pharmaceutical composition having radiosensitizing properties for administration before, during or after irradiation of a tumour for treating tumour in vivo, wherein farnesyl protein transferase inhibitor is a compound of formula (I), or compound of formula (II), or (III), which is metabolized to compound of formula (I) in vivo, wherein the dotted line represents an optional bond; X is oxygen or sulphur and other symbols have the meaning stated in claims.
申请公布号 SK284723(B6) 申请公布日期 2005.10.06
申请号 SK20000001986 申请日期 1999.06.30
申请人 JANSSEN PHARMACEUTICA N. V. 发明人 VAN GINCKEL ROBERT FRANCISCUS;FLOREN WIM JOANNA;END DAVID WILLIAM;WOUTERS WALTER BOUDEWIJN LEOPOLD
分类号 C07D401/06;A61K31/4709;A61K41/00;A61P35/00;A61P43/00;C07D401/14;C07D405/14;C07D413/14 主分类号 C07D401/06
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