Thienopyrimidines, process for preparing the same and use thereof

摘要

The present invention provides a thienopyrimidine compound, represented by the formula [wherein, R¹ is C_1-4 alkyl, R² is (1) phenyl optionally having a substituent such as amino, mono C_1-4 alkylamino and di C_1-4 alkylamino, or (2) a heterocyclic group optionally having a substituent such as amino, mono C_1-4 alkylamino and di C_1-4 alkylamino and the like, R³ is a hydrogen atom or C_1-4 alkyl, R⁴ is C_1-4 alkyl optionally having a substituent such as C_1-4 alkoxy-carbonyl, carboxyl, mono C_1-4 alkylamino and N-C_1-4 alkyl-N-C_7-10 aralkylamino and the like] or a salt thereof, which has antagonistic action for gonadotropin-releasing hormone.