发明名称 |
Novel process for the preparation of alpha-(2-4-disulfophenyl)-N-tert-butylnitrone and pharmaceutically acceptable salts thereof |
摘要 |
An integrated process for preparing alpha-(2,4-disulfophenyl)-N-tert-butylnitrone and its salts is disclosed in which N-tert-butylhydroxylamine acid addition salt is incompletely neutralised so as to leave catalytic amounts of acid and the neutralisation product is condensed with an appropriate aldehyde. |
申请公布号 |
AU783256(B2) |
申请公布日期 |
2005.10.06 |
申请号 |
AU20010027204 |
申请日期 |
2001.01.04 |
申请人 |
ASTRAZENECA AB;RENOVIS, INC. |
发明人 |
JORGEN BLIXT;HENRY KRUK;ULF LARSSON;JOHN MCGINLEY;SERGEI POUHOV;JOHN VAJDA;ALLAN WILCOX |
分类号 |
C07C291/04;C07C303/22;C07C303/32;C07C309/45;C07C309/46 |
主分类号 |
C07C291/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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