发明名称 |
Cytotoxicity mediation of cells evidencing surface expression of CD44 |
摘要 |
<p>This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB) or derivatives thereof, optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMABs of the instant invention.</p> |
申请公布号 |
AU2005226797(A1) |
申请公布日期 |
2005.10.06 |
申请号 |
AU20050226797 |
申请日期 |
2005.03.23 |
申请人 |
ARIUS RESEARCH, INC. |
发明人 |
HELEN P. FINDLAY;DAVID S. F. YOUNG;SUSAN E. HAHN |
分类号 |
A61K47/48;A61K39/395;A61K49/00;A61P35/00;C07K16/00;C07K16/28;C07K16/30;G01N33/50;G01N33/566;G01N33/567;G01N33/569;G01N33/574 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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