发明名称 N-OXIDES AND DERIVATIVES OF MELPHALAN FOR TREATING DISEASED STATES ASSOCIATED WITH HYPOXIA INDUCIBLE FACTOR.
摘要 <p>This invention relates to compounds which are N-oxides and derivatives thereof, as well as their use to treat HIF related diseases. These compounds have the general formula set out below and are used to treat a variety of diseases associated with HIF: formula (I) wherein R is an alkyl, aryl, arakyl or derivatives thereof such as CH3OCH2CH2- , CH3 CH2OCH2CH2- , C6H5OCH2CH2- , C6H5CH2- , CH3 (CH2)3OCH2CH2Cl; or any one of the formula (II), formula (III) and formula (IV).</p>
申请公布号 MXPA05004845(A) 申请公布日期 2005.10.05
申请号 MX2005PA04845 申请日期 2003.11.03
申请人 PROLX PHARMACEUTICALS CORPORATION 发明人 SARAH J. WELSH
分类号 A61K31/195;A61K31/66;C07F9/6584 主分类号 A61K31/195
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