发明名称 |
LONG-LASTING RELEASE NIFEDIPINE PREPARATION |
摘要 |
This invention provides a long-lasting release solid nifedipine preparation which exhibits clinically sufficient effect when administered once per day. A press coated tablet whose core and shell each contains nifedipine, the dissolution rate of nifedipine from said tablet being (a) in the dissolution test using a sinker according to method 2 of the dissolution test method as prescribed by the Pharmacopoeia of Japan, after 2 hours 10-40% after 4 hours 30-65% after 6 hours at least 55%, and (b) in the dissolution test according to the disintegration test method as prescribed by the Pharmacopoeia of Japan, after 3 hours 20-45% after 4 hours 30-65%.
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申请公布号 |
CA2191178(C) |
申请公布日期 |
2005.10.04 |
申请号 |
CA19962191178 |
申请日期 |
1996.11.25 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
NISHIOKA, TAKAAKI;KURATANI, KENJI;KANASAKI, HARUO;LUCHTENBERG, HELMUT;OHM, ANDREAS;TENTER, ULRICH |
分类号 |
A61K9/28;A61K9/24;A61K31/4422;A61K31/455;A61K47/32;A61K47/38;A61P9/08;A61P9/10;(IPC1-7):A61K31/44;A61K9/30 |
主分类号 |
A61K9/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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