发明名称 |
Inhibitor of human myeloid leukemia on base of asymmetric cobalt trichloroacetate dimer |
摘要 |
The invention relates to the application of coordinative combinations in medicine, namely to the use of monohydrate (m-aqua)-bis-(m-trichloroacetato)-tri(aqua)cobalt-aqua-bis-(trichloroacetato)cobalt as inhibitor of human myeloid leukemia.Summary of the invention consists in that as inhibitor of human myeloid leukemia is claimed (m-aqua)-bis-(m-trichloroacetato)-tri(aqua)cobalt-aqua-bis-(trichloroacetato)cobalt monohydrate of the formula:The result of the invention consists in the establishment at the known (m-aqua)-bis-(m-trichloroacetato)-tri(aqua)cobalt-aqua-bis-(trichloroacetato)cobalt monohydrate of the anticancer activity, exceeding 1,25...1,35 times the analogous characteristics of the dimeric trihydrate of aquaethylenediaminetetraacetatobismuthate (III) of 1,6-dimitrotetraaminecobalt (III) and dehydrate of ethylenediaminetetraacetatobismuthate (III) of oxalatotetraaminecobalt (III) (of the analogue).
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申请公布号 |
MD2851(F1) |
申请公布日期 |
2005.09.30 |
申请号 |
MD20040000199 |
申请日期 |
2004.08.12 |
申请人 |
UNIVERSITATEA DE STAT DIN MOLDOVA |
发明人 |
GULEA AURELIAN;POIRIER DONALD;ROY JENNY;POPOVSCHI LILIA;TAPCOV VICTOR |
分类号 |
A61K31/295;A61P35/02;C07C53/16;C07F15/06;(IPC1-7):A61K31/295 |
主分类号 |
A61K31/295 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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