| 摘要 |
A process of fermenting a phytosterol composition to produce androstenedione androst-4-ene-3,17-dione and subsequently androstadienedione and rosta-1,4-diene,3,17-dione comprises propagating a microbial culture of the genus Mycobacterium in a first nutrient medium, placing the microbial culture and the phytosterol composition in a bioreactor for a sufficient time to transform the composition substantially to androstenedione the "AD solution", propagating a fungal culture of the genus Fusarium in a second nutrient medium, and then injecting one or more of 1 Fusarium sp, or 2 the fungal culture medium into the bioreactor for a sufficient time to transform the AD solution to androstadienedione. |
