Methods of blocking tissue destruction by autoreactive T cells

摘要

Methods for blocking autoreactive T cell-initiated destruction of tissues in a mammal are provided. In one embodiment, the methods involve administering a pharmaceutical composition comprising an agent selected from a fusion protein comprising an HSA/CD24 polypeptide and a fusion protein comprising a biologically active fragment of an HSA/CD24 polypeptide. In some embodiments, the polypeptide or fragment is glycosylated.