| 摘要 |
Compositions, methods, and kits for detecting and monitoring kinase or phosphatase activity are described. The compositions typically include a peptide, a detectable moiety, and a protease cleavage site. Modification of a peptide by a kinase or phosphatase alters the proteolytic sensitivity of the peptide, resulting in a change of a detectable property of the composition. Panel assays for determining substrates or modulators of kinase or phosphatase activity are also described. |
| 申请人 |
INVITROGEN CORPORATION;WERNER, ELIZABETH, A.;KLINK, TONY, A;BEEBE, JANE, A.;LASKY, DAVID, A.;KLEMAN-LEYER, KAREN, M.;SOMBERG, RICHARD |
发明人 |
WERNER, ELIZABETH, A.;KLINK, TONY, A;BEEBE, JANE, A.;LASKY, DAVID, A.;KLEMAN-LEYER, KAREN, M.;SOMBERG, RICHARD |
