发明名称 Methods of identifying responders to dopamine agonist therapy
摘要 The present invention is directed to a method of identifying patients to be treated by dopamine agonist therapy comprising the step of analyzing a plasma or urine sample from said patient for concentrations of norepinephrine (NE), norepinephrine metabolites (NE metabolites), dopamine, dopamine metabolites, serotonin, serotonin metabolites, or fasting triglycerides, wherein one or more of: (a) NE metabolites, (b) NE/NE metabolites:dopamine/dopamine metabolites, (c) NE and serotonin, (d) NE/NE metabolites and serotonin, (e) NE and serotonin metabolites, (f) NE/NE metabolites and serotonin metabolites, or (g) NE is/are greater than about 30% over normal level; or dopamine/dopamine metabolites are less than about 30% below normal; or fasting triglycerides are greater than about 150 mg/dl and/or said patient has blood pressure of greater than about 135/85 mm Hg. The present invention is also directed to treating identified patients with dopamine agonist therapy.
申请公布号 US2005215558(A1) 申请公布日期 2005.09.29
申请号 US20050086937 申请日期 2005.03.22
申请人 CINCOTTA ANTHONY H 发明人 CINCOTTA ANTHONY H.
分类号 A61K31/498;G01N33/00;G01N33/68;(IPC1-7):A61K31/498 主分类号 A61K31/498
代理机构 代理人
主权项
地址