发明名称 |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF CONDITIONS RELATED TO GASTRIC ACID SECRETION |
摘要 |
<p>A method comprising orally administering to a mammal a proton pump inhibitor, or a pharmaceutically acceptable prodrug thereof, and a compound which modulates the activity of the MRP2 or other transporter proteins involved in efflux of a proton pump inhibitor or a prodrug, is disclosed herein, said method being effective for the prevention or treatment of a disease or condition related to gastric acid secretion. This method applied to compounds which both inhibit and stimulate MRP2 activity or activity of other transporter proteins involved in efflux of a proton pump inhibitor or a prodrug. Compositions, medicaments, and experimental results related thereto are also disclosed.</p> |
申请公布号 |
WO2005089758(A1) |
申请公布日期 |
2005.09.29 |
申请号 |
WO2005US07015 |
申请日期 |
2005.03.03 |
申请人 |
ALLERGAN, INC.;SHEN, JIE;WELTY, DEVIN, F.;TANG-LIU, DIANE, D. |
发明人 |
SHEN, JIE;WELTY, DEVIN, F.;TANG-LIU, DIANE, D. |
分类号 |
A61K31/4439;A61K31/4704;A61K38/06;(IPC1-7):A61K31/443;A61P1/04;A61K31/470 |
主分类号 |
A61K31/4439 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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