发明名称 |
Stable pharmaceutical composition comprising an acid labile drug |
摘要 |
The present invention provides a stable pharmaceutical composition of an acid labile drug such as a pharmaceutically active substituted benzimidazole compound, comprising: a) an inner core coated with the acid labile drug; b) a first intermediate coating devoid of an alkaline stabilizing agent and the benzimidazole compound; c) a second intermediate coating comprising an alkaline stabilizing agent; and, d) an outer enteric layer. The present invention also provides a method of preparing the same.
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申请公布号 |
US2005214371(A1) |
申请公布日期 |
2005.09.29 |
申请号 |
US20050068881 |
申请日期 |
2005.03.02 |
申请人 |
DI CAPUA SIMONA;SHTERMAN NAVA;ARI-PARDO LIMOR;ITAH ESTHER |
发明人 |
DI CAPUA SIMONA;SHTERMAN NAVA;ARI-PARDO LIMOR;ITAH ESTHER |
分类号 |
A61K9/16;A61K9/24;A61K9/50;A61K31/4439;(IPC1-7):A61K31/443 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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