发明名称 |
MEDICAL ARTICLES HAVING REGIONS WITH POLYELECTROLYTE MULTILAYER COATINGS FOR REGULATING DRUG RELEASE |
摘要 |
The medical articles which comprise the following: (a) a ceramic or metallic region whose surface comprises a plurality of depressions, (b) a multilayer coating region comprising multiple polyelectrolyte layers deposited over the surface of the ceramic or metallic region; and (c) a therapeutic agent disposed beneath or within the multilayer coating region. According to another aspect of the present invention, medical articles are provided, which comprise: (a) a ceramic or metallic region, (b) a multilayer coating region comprising multiple polyelectrolyte layers deposited over a surface of the ceramic or metallic region, the multilayer coating region comprising a plurality of protuberances; and (c) a therapeutic agent disposed within regions beneath the protuberances. Also described herein are methods of making such medical articles, and methods of administering a therapeutic agent to a patent using such medical articles. |
申请公布号 |
WO2005089825(A2) |
申请公布日期 |
2005.09.29 |
申请号 |
WO2005US09121 |
申请日期 |
2005.03.18 |
申请人 |
BOSTON SCIENTIFIC SCIMED, INC.;WEBER, JAN;NEUENDORF, RACHEL |
发明人 |
WEBER, JAN;NEUENDORF, RACHEL |
分类号 |
A61F2/00;A61F2/06;A61L31/10;A61L31/16 |
主分类号 |
A61F2/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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