摘要 |
The present invention relates a method of forming an orthotopic solid tumor in a host. The method includes the step of introducing transformed cells into an orthotopic site in the host and allowing the introduced cells to form a tumor. The cells introduced into the orthotopic site are transformed by the introduction of exogenous nucleic acid into the cells and host tissue is not removed from the orthotopic site prior to the introduction of the transformed cells into the orthotopic site.
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