The present invention relates to a simple method for generating antibody-based structures suitable for in vivo use. In particular, the invention relates to a method for the generation of antibody-based structures suitable for in vivo use comprising the steps of: (a) selecting an antibody single variable domain having an epitope binding specificity; and (b) attaching the single domain of step (a) to an effector group. Uses of molecules generated using the method of the invention are also described.
申请公布号
WO2004058820(A3)
申请公布日期
2005.09.29
申请号
WO2003GB05597
申请日期
2003.12.24
申请人
DOMANTIS LIMITED;WINTER, GREG;TOMLINSON, IAN;IGNATOVICH, OLGA;BREWIS, NEIL
发明人
WINTER, GREG;TOMLINSON, IAN;IGNATOVICH, OLGA;BREWIS, NEIL