发明名称 |
DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS |
摘要 |
<p>The invention relates to a compound having general formula (I), wherein: m = 1 to 4; n represents = 1, 2 or 3; o = 1 or 2; A is selected from among one or more X, Y and/or Z groups; X = optionally-substituted methylene; Y = C2-alkenylene, optionally substituted; Z = C3-7-cycloalkyl; B = covalent bond or C1-6-alkylene; G = covalent bond, O, S, -CH(OH)-, CO, SO or SO2; R1 represents an aryl- or heteroaryl-type group; R2 =hydrogen or C1-6-alkyl; R3 = hydrogen, C1-6-alkyl, C3-7-cycloalkyl, C3-7-cycloalkyl-C1-3-alkylene. The inventive compound takes the form of a base, an acid addition salt, a hydrate or a solvate. Said compounds are suitable for use as FAAH enzyme inhibitors.</p> |
申请公布号 |
WO2005089759(A1) |
申请公布日期 |
2005.09.29 |
申请号 |
WO2005FR00452 |
申请日期 |
2005.02.25 |
申请人 |
SANOFI-AVENTIS;ABOUABDELLAH, AHMED;ALMARIO GARCIA, ANTONIO;HOORNAERT, CHRISTIAN;JEUNESSE, JEAN |
发明人 |
ABOUABDELLAH, AHMED;ALMARIO GARCIA, ANTONIO;HOORNAERT, CHRISTIAN;JEUNESSE, JEAN |
分类号 |
C07D205/04;C07D207/09;C07D211/26;C07D211/34;C07D211/58;(IPC1-7):A61K31/446;A61K31/445;C07D207/04 |
主分类号 |
C07D205/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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