发明名称 |
HYDANTOINS HAVING RNase MODULATORY ACTIVITY |
摘要 |
<p>The present invention relates to hydantoin derivatives having RNase H, polymerase and/or HIV reverse transcriptase modulatory, and particularly, inhibitory activity. Included in the invention are the hydantoin derivatives, compositions containing the derivatives, methods of synthesis of the derivatives, screening methods to identify the derivatives, and methods of treatment using the hydantoin derivatives, including the treatment of HIV, AIDS and retrovirusassociated cancer.</p> |
申请公布号 |
WO2005090316(A1) |
申请公布日期 |
2005.09.29 |
申请号 |
WO2005US08166 |
申请日期 |
2005.03.11 |
申请人 |
WYETH;OLSON, MATTHEW, W.;DI GRANDI, MARTIN;PRASHAD, AMARNAUTH |
发明人 |
OLSON, MATTHEW, W.;DI GRANDI, MARTIN;PRASHAD, AMARNAUTH |
分类号 |
A61K31/4166;C07D233/74;C07D233/76;C07D471/10;(IPC1-7):C07D233/74;A61P31/18;A61K31/416 |
主分类号 |
A61K31/4166 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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