Therapeutic agent for rheumatic disease comprising benzamide derivative as active ingredient

摘要

The present invention provides a method of treating rheumatic diseases comprising administering to a patient a pharmaceutically effective amount of a benzamide derivative or salts thereof. The benzamide derivative is a compound represented by the following general formula [1] or a salt thereof as an active ingredient. In the formula, R¹, R² and R³, the same or different, are hydrogen, halogen, hydroxyl, lower alkyl, lower alkoxy, aryl, aryl-lower alkyl, aryloxy, amino, amino-lower alkyl, lower alkylamino or carboxyl, X is aryl or a heterocycle, Y is a direct bond or lower alkylene wherein the lower alkylene can contain oxygen atom(s) in the group, and Z is a direct bond or lower alkylene.