发明名称 |
POLYNUCLEOTIDE SYNTHESIS |
摘要 |
Methods of improving the kinetics of bimolecular interactions where reactant s are present in low concentrations are provided. Methods of pre-amplifying on e or more oligonucleotides using high concentration universal primers are provided. Methods of improving the error rate in oligonucleotide and/or polynucleotide syntheses are also provided. Methods for sequence optimizatio n and oligonucleotides design are further provided.
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申请公布号 |
CA2558749(A1) |
申请公布日期 |
2005.09.29 |
申请号 |
CA20052558749 |
申请日期 |
2005.02.28 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
CHURCH, GEORGE M.;TIAN, JINGDONG |
分类号 |
C40B40/06;C07H21/00;C12M1/40;C12N15/09;C12N15/10;C12P19/34;C12Q1/68;C40B50/06;C40B50/14;G01N33/50;G01N35/10;G06F19/00 |
主分类号 |
C40B40/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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