发明名称 COMPOSITIONS AND METHODS OF TREATING ABNORMAL CELL PROLIFERATION
摘要 A composition is described comprising a vitamin D analog and a retinoid, wherein: (a) the vitamin D analog is capable of binding a vitamin D receptor or being converted in vivo into a compound capable of binding a vitamin D receptor; and (b) the retinoid is selected from the group consisting of a compound capable of binding a retinoic acid receptor, retinol in a concentration of at least about 0.1% and a compound in a concentration of at least about 0.% capable of being converted in vivo into retinol. Further, methods of treating disorders characterized by abnormal cell-proliferation and/or cell-differentiation are also described.
申请公布号 EP1104294(B1) 申请公布日期 2005.09.28
申请号 EP19990933947 申请日期 1999.07.13
申请人 LEO PHARMA A/S 发明人 ACHKAR, CHARLES C.
分类号 A61K8/00;A61K31/07;A61K31/59;A61K45/06;A61P17/00;A61P17/06;A61P17/14;A61P43/00;A61Q5/00;A61Q7/00;A61Q19/00 主分类号 A61K8/00
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