发明名称 IMIDAZOLIC COMPOUNDS AND USE THEREOF AS ALPHA-2 ADRENERGIC RECEPTORS
摘要 4-(6-Spiro-1'-cyclopropane-1a,6-dihydro-1H-cyclopropa(a)inden-6a-yl)-1H-imidazoles (I), and their optionally hydrated mineral or organic acid addition salts, isomers (specifically the D- and L-isomers) and tautomers, are new. 4-(6-Spiro-1'-cyclopropane-1a,6-dihydro-1H-cyclopropa(a)inden-6a-yl)-1H-imidazoles of formula (I), and their optionally hydrated mineral or organic acid addition salts, isomers (specifically the D- and L-isomers) and tautomers, are new: R1 = H, F or OMe; R2 = H or Me; and R3 = H, Me or Et. An Independent claim is also included for the preparation of (I).
申请公布号 ZA200409952(B) 申请公布日期 2005.09.28
申请号 ZA20040009952 申请日期 2004.12.08
申请人 PIERRE FABRE MEDICAMENT, A FRENCH SIMPLIFIED STOCK COMPANY 发明人 Bernard VACHER;Bernard BONNAUD;Marc MARIEN;Peters PAUWELS
分类号 A61K;A61K31/4164;A61P;A61P25/02;A61P25/16;A61P25/28;A61P43/00;C07D;C07D233/54;C07D233/58;C07D233/64 主分类号 A61K
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