| 摘要 |
FIELD: medicine, pharmacy. ^ SUBSTANCE: invention relates to: (a) phenothiazine or phenothiazine analogue, or its derivative (phenothiazine material) of the formula (I): in forms of granules of spherical form mainly comprising very low amount of highly dispersed particles, and to (b) a method for preparing the phenothiazine material in forms of granules exhibiting spherical form mainly. In the formula (I) values R1, R2 and R3 are given in the invention claim. The phenothiazine material has the improved capacity for treatment, fluidity and dissolving time, minimal formation of highly dispersed particles, irritation effect and enhanced sensitivity caused by such highly dispersed particles. ^ EFFECT: improved preparing method, improved and valuable pharmaceutical properties of material. ^ 44 cl, 1 dwg, 1 tbl, 2 ex |
