发明名称 СПОСОБ ЛЕЧЕНИЯ ОНКОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЙ
摘要 The invention relates to medicine and veterinary science and can be used for treating mainly solid tumors. The inventive method for treating oncological diseases consisting in injecting a blood extracellular DNA destroying agent into a systemic blood circulation. Said blood extracellular DNA destroying agent can be embodied in the form of a DNAse enzyme, in particular a bovine pancreatic DNAse which is parenterally injected in doses ranging from of 50 000 Kunz units to 250 000 000 Kunz units a day every day during 5-360 days or in the form of a recombinant human DNAse. In addition, a blood extracellular DNA binding agent embodied in the form of anti-DNA antibodies can be injected into a systemic blood circulation. In addition a modified agent which modifies the chemical composition and/or conformation and/or polymery and/or an association with proteins and/or lipids and/or ribonucleic acids of the blood extracellular DNA. Said modifying agent can be embodied in the form of a enzyme-ribonuclease. An extracellular ribonuclease of a Serratia Mercenses bacterium can be used in the form of said agents.
申请公布号 RU2004108061(A) 申请公布日期 2005.09.27
申请号 RU20040108061 申请日期 2004.03.12
申请人 Генкин Дмитрий Дмитриевич (RU);Тец Виктор Вениаминович (RU) 发明人 Генкин Дмитрий Дмитриевич (RU);Тец Виктор Вениаминович (RU);Тец Георгий Викторович (RU)
分类号 A61K38/43;A61K38/44;A61K38/46;A61P35/00 主分类号 A61K38/43
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